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<!--'''Proboj godine'''-->'''Proboj godine''' (engl. ''Breakthrough of the Year'') godišnja je nagrada koju dodjeljuje časopis ''[[Science (časopis)|Science]]'' za najznačajniji razvoj u znanstvenom istraživanju. Inspirirana ''[[Osoba godine (Time)|Čovjekom godine]]'' magazina ''Timea'', nagrada je prvi put dodijeljena 1989. godine pod imenom ''Molekula godine'', a ime je promijenila u ''Proboj godine'' [[1996.]] godine. ''Proboj godine'' naširoko se smatra najvećim priznanjem u znanosti.
Proboj godine''' (engl. ''Breakthrough of the Year'') godišnja je nagrada koju dodjeljuje časopis ''[[Science (časopis)|Science]]'' za najznačajniji razvoj u znanstvenom istraživanju. Inspirirana ''[[Osoba godine (Time)|Čovjekom godine]]'' magazina ''Timea'', nagrada je prvi put dodijeljena 1989. godine pod imenom ''Molekula godine'', a ime je promijenila u ''Proboj godine'' [[1996.]] godine. ''Proboj godine'' naširoko se smatra najvećim priznanjem u znanosti.


== Molekula godine ==
== Molekula godine ==
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* 2010.: prvi [[kvantni stroj]]<ref>{{cite journal |author=Adrian Cho |title=BREAKTHROUGH OF THE YEAR. The First Quantum Machine |journal=[[Science (časopis)|Science]] |year=2010 |volume=330 |issue=6011 |pages=1604 |doi=10.1126/science.330.6011.1604 |bibcode=2010Sci...330.1604C}}</ref>
* 2010.: prvi [[kvantni stroj]]<ref>{{cite journal |author=Adrian Cho |title=BREAKTHROUGH OF THE YEAR. The First Quantum Machine |journal=[[Science (časopis)|Science]] |year=2010 |volume=330 |issue=6011 |pages=1604 |doi=10.1126/science.330.6011.1604 |bibcode=2010Sci...330.1604C}}</ref>
* 2011.: klinički pokus [[HPTN 052]]<ref>{{cite journal |author=Jon Cohen |title=BREAKTHROUGH OF THE YEAR. HIV Treatment as Prevention|journal=[[Science (časopis)|Science]] |year=2011 |volume=334 |issue=6063 |pages=1628 |doi=10.1126/science.334.6063.1628|bibcode =  2011Sci...334.1628C |pmid=22194547}}</ref>
* 2011.: klinički pokus [[HPTN 052]]<ref>{{cite journal |author=Jon Cohen |title=BREAKTHROUGH OF THE YEAR. HIV Treatment as Prevention|journal=[[Science (časopis)|Science]] |year=2011 |volume=334 |issue=6063 |pages=1628 |doi=10.1126/science.334.6063.1628|bibcode =  2011Sci...334.1628C |pmid=22194547}}</ref>
* 2012.: otkriće [[Higgsov bozon|Higgsova bozona]]<ref>{{cite web|url=http://www.sciencemag.org/site/special/btoy2012/|title=Breakthrough of the Year, 2012|publisher=[[Science (časopis)|Science]]}}</ref>
* 2012.: otkriće [[Higgsov bozon|Higgsova bozona]]<ref>{{Citiranje web|url=http://www.sciencemag.org/site/special/btoy2012/|title=Breakthrough of the Year, 2012|publisher=[[Science (časopis)|Science]]}}</ref>
* 2013.: [[imunoterapija raka]]<ref>{{cite web|url=http://sciencemag.org/content/342/6165/1432.full|title=Cancer Immunotherapy|author=Jenifer Couzin-Franken|publisher=Science|date=20. prosinca 2013.|accessdate=22. prosinca 2013.}}</ref>
* 2013.: [[imunoterapija raka]]<ref>{{Citiranje web|url=http://sciencemag.org/content/342/6165/1432.full|title=Cancer Immunotherapy|author=Jenifer Couzin-Franken|publisher=Science|date=20. prosinca 2013.|accessdate=22. prosinca 2013.}}</ref>
*2014.: [[Rosetta (svemirska letjelica)|Rosetta]] dolazi do kometa 67P/Churyumov–Gerasimenko <ref>{{Citiranje časopisa|author=Eric Hand|title=Comet Breakthrough of the Year + People's choice|url=http://dx.doi.org/10.1126/science.346.6216.1442|date=2014-12-18|journal=Science|volume=346|issue=6216|pages=1442–1443|id=10.1126/science.346.6216.1442|accessdate=2019-11-17}}</ref>
*2014.: [[Rosetta (svemirska letjelica)|Rosetta]] dolazi do kometa 67P/Churyumov–Gerasimenko <ref>{{Citiranje časopisa|author=Eric Hand|title=Comet Breakthrough of the Year + People's choice|url=http://dx.doi.org/10.1126/science.346.6216.1442|date=2014-12-18|journal=Science|volume=346|issue=6216|pages=1442–1443|id=10.1126/science.346.6216.1442|accessdate=2019-11-17}}</ref>
*2015.: CRISPR [[uređivanje gena]]<ref>{{Citiranje časopisa|author=J. Travis|title=Making the cut|url=http://dx.doi.org/10.1126/science.350.6267.1456|date=2015-12-17|journal=Science|volume=350|issue=6267|pages=1456–1457|id=10.1126/science.350.6267.1456|accessdate=2019-11-17}}</ref>
*2015.: CRISPR [[uređivanje gena]]<ref>{{Citiranje časopisa|author=J. Travis|title=Making the cut|url=http://dx.doi.org/10.1126/science.350.6267.1456|date=2015-12-17|journal=Science|volume=350|issue=6267|pages=1456–1457|id=10.1126/science.350.6267.1456|accessdate=2019-11-17}}</ref>

Posljednja izmjena od 24. ožujak 2022. u 04:59

Proboj godine (engl. Breakthrough of the Year) godišnja je nagrada koju dodjeljuje časopis Science za najznačajniji razvoj u znanstvenom istraživanju. Inspirirana Čovjekom godine magazina Timea, nagrada je prvi put dodijeljena 1989. godine pod imenom Molekula godine, a ime je promijenila u Proboj godine 1996. godine. Proboj godine naširoko se smatra najvećim priznanjem u znanosti.

Molekula godine[uredi]

Od 2002. godine Molekulu godine dodjeljuje Međunarodno društvo za molekularnu i staničnu biologiju i biotehnološke protokole i istraživanja (engl. International Society For Molecular and Cell Biology and Biotechnology Protocols and Researches, akr. ISMCBBPR).[7]

Proboj godine[uredi]

Izvori[uredi]

  1. ↑ R. L. Guyer and D. E. Koshland, Jr (1989). "The Molecule of the Year". Science 246 (4937): 1543–1546. doi:10.1126/science.2688087. PMID 2688087 
  2. ↑ D. E. Koshland, Jr (1990). "The Molecule of the Year". Science 250 (4988): 1637. Bibcode 1990Sci...250.1637K. doi:10.1126/science.250.4988.1637 
  3. ↑ D. E. Koshland, Jr (1991). "Molecule of the Year". Science 254 (5039): 1705. Bibcode 1991Sci...254.1705K. doi:10.1126/science.254.5039.1705 
  4. ↑ D. E. Koshland, Jr (1992). "The Molecule of the Year". Science 258 (5090): 1861. Bibcode 1992Sci...258.1861K. doi:10.1126/science.1470903. PMID 1470903 
  5. ↑ D. E. Koshland, Jr (1993). "Molecule of the Year". Science 262 (5142): 1953. Bibcode 1993Sci...262.1953K. doi:10.1126/science.8266084. PMID 8266084 
  6. ↑ D. E. Koshland, Jr (1994). "Molecule of the Year: the DNA repair enzyme". Science 266 (5193): 1925. Bibcode 1994Sci...266.1925K. doi:10.1126/science.7801114. PMID 7801114 
  7. ↑ Molecule of the Year. ISMCBBPR.
  8. ↑ Kitareewan S, Pitha-Rowe I, Sekula D, Lowrey CH, Nemeth MJ, Golub TR, Freemantle SJ, Dmitrovsky E. (2002). "UBE1L is a retinoid target that triggers PML/RARα degradation and apoptosis in acute promyelocytic leukemia". PNAS 99 (6): 3806–11. Bibcode 2002PNAS...99.3806K. doi:10.1073/pnas.052011299. PMC 122605. PMID 11891284. //www.ncbi.nlm.nih.gov/pmc/articles/PMC122605/ 
  9. ↑ Nancy J. Sullivan, Thomas W. Geisbert, Joan B. Geisbert, Ling Xu, Zhi-yong Yang, Mario Roederer, Richard A. Koup, Peter B. Jahrling and Gary J. Nabel (2000). "Development of a preventive vaccine for Ebola virus infection in primates". Nature 408 (6812): 605–9. doi:10.1038/35046108. PMID 11117750 
  10. ↑ George D Prell, Giorgio P Martinelli, Gay R Holstein, Jasenka Matulić-Adamić, Kyoichi A Watanabe, Susan L F Chan, Noel G Morgan, Musa A Haxhiu, Paul Ernsberger (2004). "Imidazoleacetic acid-ribotide: an endogenous ligand that stimulates imidazol(in)e receptors". PNAS 101 (37): 13677–13682. Bibcode 2004PNAS..10113677P. doi:10.1073/pnas.0404846101 
  11. ↑ Rosa M.F. Cardoso, Michael B. Zwick, Robyn L. Stanfield, Renate Kunert, James M. Binley, Hermann Katinger, Dennis R. Burtonand Ian A. Wilson. (2005). "Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41". Immunity 22 (2): 163–173. doi:10.1016/j.immuni.2004.12.011. PMID 15723805 
  12. ↑ Nozomu Yanaihara, Natasha Caplen, Elise Bowman, Masahiro Seike, Kensuke Kumamoto, Ming Yi, Robert M. Stephens, Aikou Okamoto, Jun Yokota, Ta dao Tanaka, George Adrian Calin, Chang-Gong Liu, Carlo M. Croce and Curtis C. Harris. (2006). "Unique microRNA molecular profiles in lung cancer diagnosis and prognosis". Cancer Cell 9 (3): 189–198. doi:10.1016/j.ccr.2006.01.025. PMID 16530703 
  13. ↑ Yoshiro Ishimaru, Hitoshi Inada, Momoka Kubota, Hanyi Zhuang, Makoto Tominaga and Hiroaki Matsunami (2006). "Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor". PNAS 103 (33): 12569–12574. Bibcode 2006PNAS..10312569I. doi:10.1073/pnas.0602702103 
  14. ↑ Stephanie Planque, Yasuhiro Nishiyama, Hiroaki Taguchi, Maria Salas, Carl Hanson and Sudhir Paul (2008). "Catalytic antibodies to HIV: Physiological role and potential clinical utility". Autoimmunity Reviews 7 (6): 473–479. doi:10.1016/j.autrev.2008.04.002. PMC 2527403. PMID 18558365. //www.ncbi.nlm.nih.gov/pmc/articles/PMC2527403/ 
  15. ↑ Mátés L, Chuah MK, Belay E, Jerchow B, Manoj N, Acosta-Sanchez A, Grzela DP, Schmitt A, Becker K, Matrai J, Ma L, Samara-Kuko E, Gysemans C, Pryputniewicz D, Miskey C, Fletcher B, Vandendriessche T, Ivics Z, Izsvák Z. (2009). "Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates". Nature Genetics 41 (6): 753–61. doi:10.1038/ng.343. PMID 19412179 
  16. ↑ Gemenetzidis E, Costea ED, Parkinson EK, Waseem A, Wan H, Teh MT. (2010). "Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1". Cancer Research 70 (22): 9515–26. doi:10.1158/0008-5472.CAN-10-2173. PMC 3044465. PMID 21062979. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3044465/ 
  17. ↑ Molecule of the Year 2010: http://ismcbbpr.synthasite.com/molyearnews.php
  18. ↑ tiskovno priopćenje Sveučilišta kraljice Marije u Londonu: http://www.qmul.ac.uk/media/news/items/smd/44466.html
  19. ↑ tiskovno priopćenje: http://www.biotechniques.com/news/2010-Molecule-of-the-Year/biotechniques-311295.html
  20. ↑ http://www.scientistsolutions.com/t23427-announcing+ismcbbpr_s+molecule+of+the+year+2011.html scientistsolutions.com
  21. ↑ Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. (2012). "Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses". Cell 151 (1): 138-152. doi:10.1016/j.cell.2012.06.054. PMID 23021221 
  22. ↑ Michael Balter (1996). "BREAKTHROUGH OF THE YEAR. New Hope in HIV Disease". Science 274 (5295): 1988–1991. Bibcode 1996Sci...274.1988.. doi:10.1126/science.274.5295.1988 
  23. ↑ Elizabeth Pennisi (1997). "BREAKTHROUGH OF THE YEAR. Cloning: The Lamb That Roared". Science 278 (5346): 2038–2039. Bibcode 1997Sci...278.2038P. doi:10.1126/science.278.5346.2038 
  24. ↑ James Glanz (1998). "BREAKTHROUGH OF THE YEAR. ASTRONOMY: Cosmic Motion Revealed". Science 282 (5397): 2156–2157. Bibcode 1998Sci...282.2156G. doi:10.1126/science.282.5397.2156a 
  25. ↑ Gretchen Vogel (1999). "BREAKTHROUGH OF THE YEAR. Capturing the Promise of Youth". Science 286 (5448): 2238–2239. doi:10.1126/science.286.5448.2238. PMID 10636772 
  26. ↑ Elizabeth Pennisi (2000). "BREAKTHROUGH OF THE YEAR. Genomics Comes of Age". Science 290 (5500): 2220–2221. doi:10.1126/science.290.5500.2220. PMID 11188701 
  27. ↑ Robert F. Service (2001). "BREAKTHROUGH OF THE YEAR. Molecules Get Wired". Science 294 (5551): 2442–2443. doi:10.1126/science.294.5551.2442. PMID 11752536 
  28. ↑ Jennifer Couzin (2002). "BREAKTHROUGH OF THE YEAR. Small RNAs Make Big Splash". Science 298 (5602): 2296–2297. doi:10.1126/science.298.5602.2296. PMID 12493875 
  29. ↑ Charles Seife (2003). "BREAKTHROUGH OF THE YEAR. Illuminating the Dark Universe". Science 302 (5653): 2038–2039. doi:10.1126/science.302.5653.2038. PMID 14684787 
  30. ↑ Richard A. Kerr (2004). "BREAKTHROUGH OF THE YEAR. On Mars, a Second Chance for Life". Science 306 (5704): 2010–2012. doi:10.1126/science.306.5704.2010. PMID 15604365 
  31. ↑ Elizabeth Culotta, Elizabeth Pennisi (2005). "BREAKTHROUGH OF THE YEAR. Evolution in Action". Science 310 (5756): 1878–1879. doi:10.1126/science.310.5756.1878. PMID 16373538 
  32. ↑ Dana Mackenzie (2006). "BREAKTHROUGH OF THE YEAR. The Poincaré Conjecture—Proved". Science 314 (5807): 1848–1849. doi:10.1126/science.314.5807.1848. PMID 17185565 
  33. ↑ Elizabeth Pennisi (2007). "BREAKTHROUGH OF THE YEAR. Human Genetic Variation". Science 318 (5858): 1842–1843. doi:10.1126/science.318.5858.1842. PMID 18096770 
  34. ↑ Gretchen Vogel (2008). "BREAKTHROUGH OF THE YEAR. Reprogramming Cells". Science 322 (5909): 1766–1767. doi:10.1126/science.322.5909.1766. PMID 19095902 
  35. ↑ Ann Gibbons (2009). "BREAKTHROUGH OF THE YEAR. Ardipithecus ramidus". Science 326 (5960): 1598–1599. Bibcode 2009Sci...326.1598G. doi:10.1126/science.326.5960.1598-a 
  36. ↑ Adrian Cho (2010). "BREAKTHROUGH OF THE YEAR. The First Quantum Machine". Science 330 (6011): 1604. Bibcode 2010Sci...330.1604C. doi:10.1126/science.330.6011.1604 
  37. ↑ Jon Cohen (2011). "BREAKTHROUGH OF THE YEAR. HIV Treatment as Prevention". Science 334 (6063): 1628. Bibcode 2011Sci...334.1628C. doi:10.1126/science.334.6063.1628. PMID 22194547 
  38. ↑ {{
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  • ↑ Eric Hand (18. prosinac 2014.). "Comet Breakthrough of the Year + People's choice". Science 346 (6216): 1442–1443. 10.1126/science.346.6216.1442. http://dx.doi.org/10.1126/science.346.6216.1442 Pristupljeno 17. studeni 2019. 
  • ↑ J. Travis (17. prosinac 2015.). "Making the cut". Science 350 (6267): 1456–1457. 10.1126/science.350.6267.1456. http://dx.doi.org/10.1126/science.350.6267.1456 Pristupljeno 17. studeni 2019. 
  • ↑ Ripples in spacetime: Science's 2016 Breakthrough of the Year. 22. prosinac 2016.. https://www.sciencemag.org/news/2016/12/ripples-spacetime-sciences-2016-breakthrough-year Pristupljeno 17. studeni 2019. 
  • ↑ Jia You. 2017's scientific Breakthrough of the Year: Colliding neutron stars. http://vis.sciencemag.org/breakthrough2017/ Pristupljeno 17. studeni 2019. 
  • ↑ Jia You. Science’s 2018 Breakthrough of the Year: tracking development cell by cell. https://vis.sciencemag.org/breakthrough2018/ Pristupljeno 17. studeni 2019. 
  • ↑ Science’s 2019 Breakthrough: First Image of Supermassive Black Hole. https://www.aaas.org/news/sciences-2019-breakthrough-first-image-supermassive-black-hole Pristupljeno 28. siječanj 2020. 
    • v • r • u
    Proboj godine
    časopis Science
    1996.: razumijevanje HIV-a · 1997.: ovca Dolly · 1998.: akcelerantni svemir i tamna tvar · 1999.: matična stanica · 2000.: sekvenciranje čitava genoma · 2001.: nanokrugovi ili molekularni krug · 2002.: interferencija RNA · 2003.: tamna energija · 2004.: rover Spirit · 2005.: evolucija na djelu · 2006.: dokaz Poincaréove slutnje · 2007.: varijacija čovječjih gena · 2008.: stanično reprogramiranje · 2009.: Ardipithecus ramidus · 2010.: prvi kvantni stroj · 2011.: klinički pokus HPTN 052 · 2012.: otkriće Higgsova bozona · 2013.: imunoterapija raka  · 2014.: svemirska letjelica Rosetta  · 2015.: CRISPR uređivanje gena  · 2016.: promatranje gravitacijskih valova  · 2017.: Spajanje neutronske zvijezde (GW170817)  · 2018.: sekvenciranje pojedinačnih stanica  · 2019.: prva slika crne rupe
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