Mišji coronavirus

Izvor: Hrvatska internetska enciklopedija
Skoči na:orijentacija, traži

Mišji koronavirus (M-CoV) je vrsta koronavirusa koji zaražava miševe.[1][2] To je jednolančani RNK virus, s pozitivnim osjećajem, koji ulazi u stanicu domaćina vezanjem na CEACAM1 receptor. Kao i drugi koronavirusi iz roda Betacoronavirus, subgenus Embecovirus, ima dodatni gen hemaglutinin esteraze (HE).

Značajka MHV-a[3], aka murine hepatitis virus[4] je ta što su mnogi sojevi gena hemaglutinin-esteraze pretvorili u pseudogen. To se, međutim, ne odnosi na M-CoV općenito, jer ostali članovi poput PV (Puffinosis koronavirus) zadržavaju funkcionalnu verziju ovog gena.

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Izvori

  1. PREUSMJERI Predložak:Izvori
  1. "Taxonomy browser (Murine coronavirus)". https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=694005&lvl=3&lin=f&keep=1&srchmode=1&unlock Pristupljeno 1. ožujka 2020. 
  2. Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (24. kolovoza 2010.). "Coronavirus Genomics and Bioinformatics Analysis". Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3185738/. "Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein." 
  3. ICTV 2nd Report Fenner, F. (1976). Classification and nomenclature of viruses. Second report of the International Committee on Taxonomy of Viruses. Intervirology 7: 1-115. https://talk.ictvonline.org/ictv/proposals/ICTV%202nd%20Report.pdf
  4. de Groot, Raoul J. (2009). "Revision of the family Coronaviridae" (engl.). str. 36. Inačica izvorne stranice arhivirana 7. veljače 2019.. https://talk.ictvonline.org/ictv/proposals/2008.085-122V.v4.Coronaviridae.pdf Pristupljeno 23. siječnja 2020.. "Species Murine hepatitis virus; Puffinosis coronavirus; Rat coronavirus (these are to be united in a new species Murine coronavirus in a new genus Betacoronavirus)"