Merbecovirus

Merbecovirus je potporodica virusa iz roda Betacoronavirus. Virusi iz ovog podgena su prethodno bili poznati kao koronavirusi grupe 2c.^[1]^[2]

Struktura

Virusi ovog podgene, kao i drugi koronavirusi, imaju omotnicu lipidnog dvosloja u kojoj su usidreni strukturni proteini membrane (M), ovojnice (E) i šiljka (S).^[3]^[4]

Vrste

MERS-CoV (Bliskoistočni Respiratorni Sindrom Koronavirus)
Ježev coronavirus 1
Pipistrellus šišmiš coronavirus HKU5
Tylonycteris šišmiš coronavirus HKU4

Vidi još

Izvori

↑ Woo, Patrick C. Y.; Wang, Ming; Lau, Susanna K. P.; Xu, Huifang; Poon, Rosana W. S.; Guo, Rongtong; Wong, Beatrice H. L.; Gao, Kai et al. (veljače 2007). "Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features". Journal of Virology 81 (4): 1574–1585. doi:10.1128/JVI.02182-06. ISSN 0022-538X. PMC 1797546. PMID 17121802. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1797546/. "See figure 2."
↑ Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (20. veljače 2019.). "Global Epidemiology of Bat Coronaviruses". Viruses 11 (2): 174. doi:10.3390/v11020174. ISSN 1999-4915. PMC 6409556. PMID 30791586. //www.ncbi.nlm.nih.gov/pmc/articles/PMC6409556/. "CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2]."
↑ Lai, Michael M. C.; Cavanagh, David (1. siječnja 1997.), Maramorosch, Karl; Murphy, Frederick A.; Shatkin, Aaron J., eds., "The Molecular Biology of Coronaviruses; III. Structure of Virions; A. Virion Morphology" (engl.), Advances in Virus Research (Academic Press) 48: str. 5–6, http://www.sciencedirect.com/science/article/pii/S0065352708602869, pristupljeno 28. veljače 2020.
↑ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (24. kolovoza 2010.). "Coronavirus Genomics and Bioinformatics Analysis". Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3185738/. "The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus."

[1] Woo, Patrick C. Y.; Wang, Ming; Lau, Susanna K. P.; Xu, Huifang; Poon, Rosana W. S.; Guo, Rongtong; Wong, Beatrice H. L.; Gao, Kai et al. (veljače 2007). "Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features". Journal of Virology 81 (4): 1574–1585. doi:10.1128/JVI.02182-06. ISSN 0022-538X. PMC 1797546. PMID 17121802. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1797546/. "See figure 2."

[2] Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (20. veljače 2019.). "Global Epidemiology of Bat Coronaviruses". Viruses 11 (2): 174. doi:10.3390/v11020174. ISSN 1999-4915. PMC 6409556. PMID 30791586. //www.ncbi.nlm.nih.gov/pmc/articles/PMC6409556/. "CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2]."

[:1-3] Lai, Michael M. C.; Cavanagh, David (1. siječnja 1997.), Maramorosch, Karl; Murphy, Frederick A.; Shatkin, Aaron J., eds., "The Molecular Biology of Coronaviruses; III. Structure of Virions; A. Virion Morphology" (engl.), Advances in Virus Research (Academic Press) 48: str. 5–6, http://www.sciencedirect.com/science/article/pii/S0065352708602869, pristupljeno 28. veljače 2020.

[:02-4] Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (24. kolovoza 2010.). "Coronavirus Genomics and Bioinformatics Analysis". Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3185738/. "The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus."

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