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<!--'''Embecovirus'''-->'''Embekovirus''' je subgenus koronavirusa u rodu [[Betacoronavirus]]. [[Virusi]] u ovom podgenusu, za razliku od drugih [[Coronavirus|koronavirusa]], imaju gen za [[Hemaglutinin esteraza|hemaglutinin esterazu (HE)]]. Virusi u subgenusu prethodno su bili poznati kao '''koronavirusi grupe 2a'''.<ref>{{ | <!--'''Embecovirus'''-->'''Embekovirus''' je subgenus koronavirusa u rodu [[Betacoronavirus]]. [[Virusi]] u ovom podgenusu, za razliku od drugih [[Coronavirus|koronavirusa]], imaju gen za [[Hemaglutinin esteraza|hemaglutinin esterazu (HE)]]. Virusi u subgenusu prethodno su bili poznati kao '''koronavirusi grupe 2a'''.<ref>{{Citiranje časopisa|last=Woo|first=Patrick C. Y.|last2=Wang|first2=Ming|last3=Lau|first3=Susanna K. P.|last4=Xu|first4=Huifang|last5=Poon|first5=Rosana W. S.|last6=Guo|first6=Rongtong|last7=Wong|first7=Beatrice H. L.|last8=Gao|first8=Kai|last9=Tsoi|first9=Hoi-wah|last10=Huang|first10=Yi|last11=Li|first11=Kenneth S. M.|date=February 2007|title=Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features|journal=Journal of Virology|volume=81|issue=4|pages=1574–1585|doi=10.1128/JVI.02182-06|issn=0022-538X|pmc=1797546|pmid=17121802|quote=See figure 2.}}</ref><ref>{{Citiranje časopisa|last=Wong|first=Antonio C. P.|last2=Li|first2=Xin|last3=Lau|first3=Susanna K. P.|last4=Woo|first4=Patrick C. Y.|date=2019-02-20|title=Global Epidemiology of Bat Coronaviruses|journal=Viruses|volume=11|issue=2|pages=174|doi=10.3390/v11020174|issn=1999-4915|pmc=6409556|pmid=30791586|quote=CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2].}}</ref> | ||
== Struktura == | == Struktura == | ||
Virusi ovog podgene, kao i drugi koronavirusi, imaju omotnicu lipidnog dvosloja u kojoj su usidreni strukturni proteini membrane (M), ovojnice (E) i šiljka (S). Za razliku od [[Coronaviridae|drugih koronavirusa]], virusi u ovom podgenusu također imaju dodatni kraći strukturni protein sličan šiljaku koji se zove hemaglutinin esteraza (HE).<ref name=":0">{{ | Virusi ovog podgene, kao i drugi koronavirusi, imaju omotnicu lipidnog dvosloja u kojoj su usidreni strukturni proteini membrane (M), ovojnice (E) i šiljka (S). Za razliku od [[Coronaviridae|drugih koronavirusa]], virusi u ovom podgenusu također imaju dodatni kraći strukturni protein sličan šiljaku koji se zove hemaglutinin esteraza (HE).<ref name=":0">{{Citiranje časopisa|last=Woo|first=Patrick C. Y.|last2=Huang|first2=Yi|last3=Lau|first3=Susanna K. P.|last4=Yuen|first4=Kwok-Yung|date=2010-08-24|title=Coronavirus Genomics and Bioinformatics Analysis|journal=Viruses|volume=2|issue=8|pages=1804–1820|doi=10.3390/v2081803|issn=1999-4915|pmc=3185738|pmid=21994708|quote=In all members of Betacoronavirus subgroup A, a haemagglutinin esterase (HE) gene, which encodes a glycoprotein with neuraminate O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1).}}</ref><ref name=":02">{{Citiranje časopisa|last=Woo|first=Patrick C. Y.|last2=Huang|first2=Yi|last3=Lau|first3=Susanna K. P.|last4=Yuen|first4=Kwok-Yung|date=2010-08-24|title=Coronavirus Genomics and Bioinformatics Analysis|journal=Viruses|volume=2|issue=8|pages=1804–1820|doi=10.3390/v2081803|issn=1999-4915|pmc=3185738|pmid=21994708|quote=The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus.}}</ref> | ||
== Vidi još == | == Vidi još == | ||
Posljednja izmjena od 17. prosinac 2021. u 12:49
Embekovirus je subgenus koronavirusa u rodu Betacoronavirus. Virusi u ovom podgenusu, za razliku od drugih koronavirusa, imaju gen za hemaglutinin esterazu (HE). Virusi u subgenusu prethodno su bili poznati kao koronavirusi grupe 2a.[1][2]
Struktura
Virusi ovog podgene, kao i drugi koronavirusi, imaju omotnicu lipidnog dvosloja u kojoj su usidreni strukturni proteini membrane (M), ovojnice (E) i šiljka (S). Za razliku od drugih koronavirusa, virusi u ovom podgenusu također imaju dodatni kraći strukturni protein sličan šiljaku koji se zove hemaglutinin esteraza (HE).[3][4]
Vidi još
Izvori
- PREUSMJERI Predložak:Izvori
- ↑ Woo, Patrick C. Y.; Wang, Ming; Lau, Susanna K. P.; Xu, Huifang; Poon, Rosana W. S.; Guo, Rongtong; Wong, Beatrice H. L.; Gao, Kai et al. (veljača 2007). "Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features". Journal of Virology 81 (4): 1574–1585. doi:10.1128/JVI.02182-06. ISSN 0022-538X. PMC 1797546. PMID 17121802. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1797546/. "See figure 2."
- ↑ Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (20. veljača 2019.). "Global Epidemiology of Bat Coronaviruses". Viruses 11 (2): 174. doi:10.3390/v11020174. ISSN 1999-4915. PMC 6409556. PMID 30791586. //www.ncbi.nlm.nih.gov/pmc/articles/PMC6409556/. "CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2]."
- ↑ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (24. kolovoz 2010.). "Coronavirus Genomics and Bioinformatics Analysis". Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3185738/. "In all members of Betacoronavirus subgroup A, a haemagglutinin esterase (HE) gene, which encodes a glycoprotein with neuraminate O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1)."
- ↑ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (24. kolovoz 2010.). "Coronavirus Genomics and Bioinformatics Analysis". Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3185738/. "The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus."