(+)-Alfa-barbatenska sintaza

{{#invoke:Infobox|infobox}} (+)-Alfa-barbatenska sintaza (EC 4.2.3.69, AtBS) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira (+)-alfa-barbaten).<ref>Wu, S., Schoenbeck, M.A., Greenhagen, B.T., Takahashi, S., Lee, S., Coates, R.M. and Chappell, J. (2005). "Surrogate splicing for functional analysis of sesquiterpene synthase genes". Plant Physiol. 138: 1322-1333. PMID 15965019 </ref><ref>Tholl, D., Chen, F., Petri, J., Gershenzon, J. and Pichersky, E. (2005). "Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers". Plant J. 42: 757-771. PMID 15918888 </ref> Ovaj enzim katalizira sljedeću kemijsku reakciju

(2E,6E)-farnezil difosfat <math>\rightleftharpoons</math> (+)-alfa-barbaten + difosfat

Rekombinirajući enzim iz biljke Arabidopsis thaliana formira 27.3% alfa-barbatena, 17.8% tujopsena i 9.9% beta-hamigrena.

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third ed.). USA: Oxford University Press. ISBN 019850229X . http://books.google.com/books/about/Fundamentals_of_enzymology.html?id=8uvwAAAAMAAJ 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 ed.). Wiley-Interscience. ISBN 0471205036 . http://books.google.com/books/about/Advances_in_Enzymology_and_Related_Areas.html?id=Pmh8yToeuloC 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0815323050 . http://www.garlandscience.com/textbooks/0815323042.asp?type=reviews 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 ed.). Wiley Classics Library. ISBN 0471303097 . http://books.google.com/books/about/Enzyme_Kinetics.html?id=T60oAAAAYAAJ 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd ed.). Wiley-Interscience. ISBN 111848813X . http://books.google.com/books/about/Evaluation_of_Enzyme_Inhibitors_in_Drug.html?id=l2rMy8QNUk0C 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd ed.). Wiley. ISBN 0470146842 . http://books.google.com/books/about/Biochemical_pathways.html?id=081qAAAAMAAJ 

Vanjske poveznice

• MeSH (+)-alpha-barbatene+synthase